i-STAT System controls and calibration verification materials are validated for use only with the i-STAT System and assigned values may not be commutable with other methods. Creatinine values assigned to i-STAT s controls and calibration verification materials are traceable to the National Institute of Standards and Technology (NIST) standard reference material SRM909. Creatinine Amidohydrolase Microbial Sarcosine Oxidase Microbial UCSF Clinical Labs of 6 Proc/ iSTAT /Creat.ģ Metrological Traceability The i-STAT System test for Creatinine measures Creatinine amount-of-substance concentration in the plasma fraction of arterial, venous, or capillary whole blood (dimension mol L-1) for in vitro diagnostic use. For cartridges that contain a sensor for the measurement of Creatinine, a list of reactive ingredients is indicated below: i stat Creatinine Chemistry China Basin Reactive Ingredient Biological Source Creatinine N/A Creatine Amidinohydrolase Actinobacillus sp. Contents Each i-STAT cartridge contains one reference electrode (when potentiometric sensors are included in the cartridge configuration), sensors for the measurement of specific analytes, and a buffered aqueous calibrant solution that contains known concentrations of analytes and preservatives. Certain substances, such as drugs, may affect analyte levels in If results appear inconsistent with the clinical assessment, the patient sample should be retested using another cartridge.Ģ INTENDED USE The test for Creatinine, as part of the i-STAT System, is intended for use in the in vitro quantification of Creatinine in arterial, venous, or capillary whole blood. See below for information on factors affecting results. The liberated hydrogen peroxide is oxidized at the platinum electrode to produce a current which is proportional to the sample Creatinine concentration. The oxidation of sarcosine, catalyzed by the enzyme sarcosine oxidase, produces hydrogen peroxide (H2O2). Creatine is then hydrolyzed to sarcosine in a reaction catalyzed by the enzyme creatine amidinohydrolase. Creatinine is hydrolyzed to creatine in a reaction catalyzed by the enzyme Creatinine amidohydrolase. Metrological Traceability The i-STAT System test for creatinine measures creatinine amount-of-substanceġ UCSF Clinical Labs of 6 Proc/ iSTAT /Creat. UCSF Clinical Labs of 6 Proc/ iSTAT/Creat. Certain substances, such as drugs, may affect analyte levels in If results appear inconsistent with the clinical assessment, the patient sample should be retested using another cartridge.
UCSF Clinical Labs of 6 Proc/ iSTAT /Creat. Example: bachelor of science Search Creatinine iSTAT methodology sheet - UCSF …
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